Top Scientific Research Papers


Jensen, T. K., Swan, S., Jørgensen, N., Toppari, J., Redmon, B., Punab, M., Drobnis, E. Z., Haugen, T. B., Zilaitiene, B., Sparks, A. E., Irvine, D. S., Wang, C., Jouannet, P., Brazil, C., Paasch, U., Salzbrunn, A., Skakkebæk, N. E. and Andersson, A. M. (2014) Alcohol and male reproductive health: a cross-sectional study of 8344 healthy men from Europe and the USA. Human Reproduction, 29(8): 1801–1809

Jensen, T. K., Gottschau, M., Madsen, J. O., Andersson, A. M., Lassen, T. H., Skakkebæk, N. E., Swan, S., Priskorn, L., Juul, A. and Jørgensen, N. (2014) Habitual alcohol consumption associated with reduced semen quality and changes in reproductive hormones; a cross-sectional study among 1221 young Danish men. BMJ Open, 4(9):e005462. doi:10.1136/bmjopen-2014-005462 1

DNA testing

Simon, L., Aston, K. I., Emery, B. R., Hotaling, J. and Carell, D. T. (2016) Sperm DNA damage output parameters measured by the alkaline Comet assay and their importance. Andrologia, doi:10.1111/and.12608

Simon, L., Zini, A., Dyachenko, A., Ciampi, A. and Carrell, D. T. (2016) A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome. Asian Journal of Andrology, 18: 1-11

Esteves, S. C., Sánchez-Martín, F., Sánchez-Martín, P., Schneider, D. T. and Gosálvez, J. (2015) Comparison of reproductive outcome in oligozoospermic men with high sperm DNA fragmentation undergoing intracytoplasmic sperm injection with ejaculated and testicular sperm. Fertility and Sterility, 104(6): 1398-1405

Mehta, A., Bolyakov, A., Schlegel, P. N. and Paduch, D. A. (2015) Higher pregnancy rates using testicular sperm in men with severe oligospermia. Fertility and Sterility, 0015-0282

Smith, A. D., Tilling, K., Nelson, S. M. and Lawlor, D. A. (2015) Live-Birth Rate Associated With Repeat In Vitro Fertilization Treatment Cycles. JAMA, 314(24): 2654-2662

Eisenberg, M. L., Li, S., Behr, B., Cullen, M. R., Galusha, D., Lamb, D. J. and Lipshultz, L. I. (2014) Semen quality, infertility and mortality in the USA. Human Reproduction, 29(7): 1567–1574

Zhao, J., Zhang, Q., Wang, Y. and Li, Y. (2014) Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis. Fertility and Steritility, 102(4): 998-1005.e8

Grover, S., Shmorgun, Z., Moskovtsev, S. I., Baratz, A. and Librach, C. L. (2013) Assisted reproduction in a cohort of same-sex male couples and single men. Reproductive Biomedicine Online, 27: 217– 221

Lewis, S. E. M. (2013) The place of sperm DNA fragmentation testing in current day fertility management. Middle East Fertility Society Journal Online, 18(2): 78-82

Lewis S. E. M., Aitken, R. J., Conner, S. J., De Iuliis, G., Evenson, D. P., Henkel, R., Giwercman, A. and Gharagozloo, P. (2013) The impact of sperm DNA damage in assisted conception and beyond: Recent advances in diagnosis and treatment. Reproductive BioMedicine Online, 27: 325– 337

Simon, L., Proutski, I., Stevenson, M., Jennings, D., McManus, J., Lutton, D. and Lewis, S. (2013) Sperm DNA damage has negative association with live birth rates after IVF. Reproductive Biomedicine Online, 26: 68–78

Tomlinson, M., Lewis, S. E. M. and Morroll, D. (2013) Sperm quality and its relationship to natural and assisted conception: British Fertility Society Guidelines for Andrology practice. Human Fertility, 1–19

Lewis, S. E. M., Rapino, C., Di Tommaso, M., Pucci, M., Battista, N., Paro, R., Simon, L., Lutton, D. and Maccarrone, M. (2012) Differences in the Endocannabinoid System of Sperm from Fertile and Infertile Men. PLOS One, 7(10): 1-8

Lewis, S. E. M., Paro, R., Borriello, L., Simon, L., Robinson, L., Dincer,  Z.,  Riedel, G., Battista, N. and Maccarrone, M. (2012) Long-Term Use of HU210 Adversely Affects Spermatogenesis in Rats by modulating the Endocannabinoid System. International Journal Andrology, 35 (5): 731-40

Robinson, L., Gallos, I. D., Connor, S. J., Rajkhowa, M., Miller, D., Lewis, S. E. M., Kirkman-Brown, J. and Coomarasamy, A. (2012) The effects of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis. Human Reproduction, 27(10): 2908-2917

Castillo, J., Simon, L., De Mateo, S., Ballescà, J. L., Lewis, S. E. M. and Oliva, R. (2011) Protamine/DNA ratios and DNA damage in native and density gradient centrifugated sperm from infertile patients. Journal of Andrology, (2011) 32:324-332

Simon, L., Castillo, J., Oliva, R., Lewis, S. E. M. (2011) The relationship between human sperm protamines, DNA damage and assisted reproductive outcomes. Fertility and Sterility, 23: 724-734

Simon, L. and Lewis, S. E. M. (2011) Sperm DNA damage or progressive motility: which one is the better predictor of fertilization in vitro? Systems Biology in Reproductive Medicine, (2011) 0: 1–6

Simon, L., Lutton, D., McManus, J. and Lewis, S. E. M. (2011) Sperm DNA damage measured by the alkaline Comet assay as an independent predictor of male infertility and IVF success. Fertility and Sterility, 95(2): 652-657

Barratt C. L. R., Aitken, R. J., de Boer, P.,  Björndahl, L., Carrell, D. T., Perreault, S. D., Kvist, U., Lewis, S. E. M., Perry, M. J., Ramos, L., Robaire. B., Ward, S. and Zini, A. (2010) Sperm DNA: organization, protection and vulnerability: from basic science to clinical applications. A position report. Reproduction, 25: 824-838

Lewis, S. E. M. and Simon, L. (2010) Clinical implications of sperm DNA damage. Human Fertility, 13(4): 201-207

Simon, L., Lutton, D., McManus, J. and Lewis, S. E. M. (2010) Clinical significance of sperm DNA damage in reproductive outcome. Human Reproduction, 25(7): 1594-1608

World Health Organization (2010) WHO laboratory manual for the examination and processing of human semen Fifth edition

Lewis, S. E. M., Alvarez, J. and Agbaje I. M. (2008) Using the alkaline comet assay in prognostic tests for male infertility and assisted reproductive technology outcomes. Systems Biology in Reproductive BioMedicine Online, 54: 111-125

Lewis, S. E. M. (2007) Is sperm evaluation useful in predicting human fertility? Reproduction, 134: 31-40

Aitken, R. J., Koopman, P. and Lewis, S. E. M. (2004) Male germs of Concern. Nature, 4(432): 48-52

Lewis, S. E. M., O’Connell, M., Stevenson, M., Thompson-Cree, L. and McClure, N. (2004) An algorithm to predict pregnancy in assisted conception. Molecular Human Reproduction, 19(6): 1385-1394

Steele, E. K., McClure, N. and Lewis, S. E. M. (2000) Comparison of the effects of two methods of cryopreservation on testicular sperm DNA. Fertility and Sterility, 74(3): 450-453

Anderson, L., Lewis, S. E. M. and McClure, N. (1998) The effects of coital lubricants on sperm motility in vitro. Human Reproduction, 13(12): 3351-3356.